RESEARCH INTERESTS
Dendrites are the physical site of the majority of synaptic contacts and play a central role in shaping cellular input-output transformations. Cortical dendrites are longer in humans than in other species, but their functional properties remain unknown. Combining dendritic patch-clamp recordings with two-photon imaging and biophysical modeling, I investigate how the size of human neurons impacts synaptic integration and the computations performed by individual neurons.
PUBLICATIONS
Enhancing circadian clock function in cancer cells inhibits tumor growth. BMC Biology, 2017
Widespread and Highly Correlated Somato-dendritic Activity in Cortical Layer 5 Neurons. Neuron, 2019