RESEARCH INTERESTS

Dendrites are the physical site of the majority of synaptic contacts and play a central role in shaping cellular input-output transformations. Cortical dendrites are longer in humans than in other species, but their functional properties remain unknown. Combining dendritic patch-clamp recordings with two-photon imaging and biophysical modeling, I investigate how the size of human neurons impacts synaptic integration and the computations performed by individual neurons.

PUBLICATIONS

Dendritic Spines Prevent Synaptic Voltage Clamp. Neuron, 2018                  

Recommended-by-Prof-Gordon-Fain-on-F1000
Recommended-by-Prof-Gordon-Fain-on-F1000

Enhanced Dendritic Compartmentalization in Human Cortical Neurons. Cell, 2018